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Promotion of Ros-mediated Bax/Cyt-c apoptosis by polyphyllin II leads to suppress growth and aggression of glioma cells
BACKGROUND: Gliomas remain among the most difficult cancers to treat, with a 5-year overall survival no greater than 5%. Many saponins showed a wide spectrum of anti-cancer activities at low concentration. Polyphyllin II is one of the common saponins from Paris polyphylla. However, the effect of Pol...
Autores principales: | Cheng, Guang, Xue, Yu-Ye, Fang, Fei, Sun, Guang-Qiang, Lu, Yun-Yang, Ji, Yu-Qiang, Qiu, Peng-Cheng, Tang, Hai-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797898/ https://www.ncbi.nlm.nih.gov/pubmed/35116689 http://dx.doi.org/10.21037/tcr-21-966 |
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