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IL-10 promoter hypomethylation is associated with increased IL-10 expression and poor survival in hepatocellular carcinoma

BACKGROUND: Epigenetic alterations of tumor-associated genes contribute to the pathogenesis of virtually all cancer types. We evaluated the methylation status of the interleukin-10 (IL-10) gene promoter and assessed its association with IL-10 mRNA expression and clinical prognosis in hepatocellular...

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Detalles Bibliográficos
Autores principales: Zhang, Xianjing, Lu, Mingzhu, Xu, Yun, He, Guangzhao, Liu, Qian, Zhu, Jing, Zhang, Changsong, Zhang, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797925/
https://www.ncbi.nlm.nih.gov/pubmed/35116889
http://dx.doi.org/10.21037/tcr.2019.07.33