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A special prognostic indicator: tumor mutation burden combined with immune infiltrates in lung adenocarcinoma with TP53 mutation

BACKGROUND: TP53 mutation (TP53(mut)) is significantly associated with immunotherapy response in lung adenocarcinoma (LUAD), but not an ideal independent prognostic predictor for it. Here, we investigated a novel potential biomarker and constructed a model for prognostic prediction in LUAD TP53(mut)...

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Detalles Bibliográficos
Autores principales: Fu, Jing, Li, Yaonan, Li, Cuidan, Tong, Yuyang, Li, Mengyuan, Cang, Shundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797931/
https://www.ncbi.nlm.nih.gov/pubmed/35116695
http://dx.doi.org/10.21037/tcr-21-565