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Knockout of LATS1 induces neoplastic phenotype in hepatic oval cells

BACKGROUND: Primary liver cancer (PLC) is the second leading cause of cancer-related death worldwide. It has been reported that PLC can be originated from malignant transformed adult hepatic progenitor cells. Mammalian large tumor suppressor kinase 1 (LATS1) is one of the core components of the Hipp...

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Detalles Bibliográficos
Autores principales: Sun, Qigang, Wu, Changxiong, Fu, Cexiong, Chen, Pingping, Chen, Cheng, Liu, Jun, Li, Shibing, Zheng, Jinfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798110/
https://www.ncbi.nlm.nih.gov/pubmed/35117720
http://dx.doi.org/10.21037/tcr-19-2847