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Acid-induced autophagy protects human gastric cancer cells from apoptosis by activating Erk1/2 pathway

BACKGROUND: Acidic microenvironments exist widely in tumors. However, the specific mechanism of cancer cell survival under an acidic microenvironment remains unknown. This study aims to investigate whether acid can induce autophagy and examine the mechanism of autophagy in gastric cancer cells. METH...

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Qi, Weiwei, Liu, Shihai, Zhao, Shufen, Lv, Jing, Qiu, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798117/
https://www.ncbi.nlm.nih.gov/pubmed/35116899
http://dx.doi.org/10.21037/tcr.2019.07.42