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Gene Therapy Potential for Genetic Disorders of Surfactant Dysfunction

Pulmonary surfactant is critically important to prevent atelectasis by lowering the surface tension of the alveolar lining liquid. While respiratory distress syndrome (RDS) is common in premature infants, severe RDS in term and late preterm infants suggests an underlying genetic etiology. Pathogenic...

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Detalles Bibliográficos
Autores principales: Cooney, Ashley L., Wambach, Jennifer A., Sinn, Patrick L., McCray, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798122/
https://www.ncbi.nlm.nih.gov/pubmed/35098209
http://dx.doi.org/10.3389/fgeed.2021.785829