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IL-27/IL-27RA signaling may modulate inflammation and progression of benign prostatic hyperplasia via suppressing the LPS/TLR4 pathway

BACKGROUND: Benign prostatic hyperplasia (BPH) is the most common urologic disease affecting aging men. The pathogenesis of BPH is multi-factorial, and chronic inflammation (CI) might be the central mechanism. Interleukin (IL)-27 signaling has been suggested as a modulator in autoimmune and inflamma...

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Detalles Bibliográficos
Autores principales: Lo, Hua-Cheng, Yu, Dah-Shyong, Gao, Hong-Wei, Tsai, Mong-Hsun, Chuang, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798123/
https://www.ncbi.nlm.nih.gov/pubmed/35117826
http://dx.doi.org/10.21037/tcr-20-1509