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Tamoxifen side effects: pharmacogenetic and clinical approach in Mexican mestizos

BACKGROUND: Tamoxifen metabolism is translated into four genetic phenotypes (GP): genetic poor metabolizer (gPM); genetic intermediate metabolizer (gIM); genetic normal metabolizer (gNM); and genetic ultra-rapid metabolizer (gUM). Although CYP2D6 is involved in tamoxifen biotransformation, its assoc...

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Detalles Bibliográficos
Autores principales: Rangel-Méndez, Jorge-Aarón, Rubi-Castellanos, Rodrigo, Sánchez-Cruz, Juan-Francisco, Moo-Puc, Rosa Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798170/
https://www.ncbi.nlm.nih.gov/pubmed/35116730
http://dx.doi.org/10.21037/tcr.2018.12.27