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Complex genetic alterations contribute to rapid disease progression in an ALK rearrangement lung adenocarcinoma patient: a case report

Anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK-TKIs) have been found to significantly improve the quality of life and survival in ALK-positive non-small cell lung cancer (NSCLC) patients. However, the duration of responses is limited by drug resistance. Genetic heterogeneity of ALK-posit...

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Detalles Bibliográficos
Autores principales: Long, Xiang, Wu, Hao, Yang, Chenglin, Li, Fang, Zhang, Min, Wu, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798290/
https://www.ncbi.nlm.nih.gov/pubmed/35116617
http://dx.doi.org/10.21037/tcr-20-3473