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Metallothionein 1M (MT1M) inhibits lung adenocarcinoma cell viability, migration, and expression of cell mobility-related proteins through MDM2/p53/MT1M signaling

BACKGROUND: Metallothionein 1M (MT1M) functions to regulate cell proliferation and cancer metastasis. This study assessed the effects of MT1M overexpression and mouse double minute 2 homolog (MDM2) knockdown on the regulation of non-small cell lung cancer A549 cell viability, migration, and protein...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Jiang, Guo-Jun, Shi, Guo-Zhen, Chen, Ming-Zhi, Ma, Tie-Liang, Tan, Yong-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798298/
https://www.ncbi.nlm.nih.gov/pubmed/35117630
http://dx.doi.org/10.21037/tcr.2020.02.61