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Metallothionein 1M (MT1M) inhibits lung adenocarcinoma cell viability, migration, and expression of cell mobility-related proteins through MDM2/p53/MT1M signaling
BACKGROUND: Metallothionein 1M (MT1M) functions to regulate cell proliferation and cancer metastasis. This study assessed the effects of MT1M overexpression and mouse double minute 2 homolog (MDM2) knockdown on the regulation of non-small cell lung cancer A549 cell viability, migration, and protein...
Autores principales: | Xu, Wei, Jiang, Guo-Jun, Shi, Guo-Zhen, Chen, Ming-Zhi, Ma, Tie-Liang, Tan, Yong-Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798298/ https://www.ncbi.nlm.nih.gov/pubmed/35117630 http://dx.doi.org/10.21037/tcr.2020.02.61 |
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