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Metformin suppressed tumor necrosis factor-α-induced epithelial-mesenchymal transition in prostate cancer by inactivating the NF-κB signaling pathway

BACKGROUND: Epithelial-mesenchymal transition (EMT) and the tumor micro- environment are involved in tumorigenesis and progression. Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine in cancer that might be associated with promoting cancer invasion and metastasis. This study aimed to expl...

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Detalles Bibliográficos
Autores principales: Wang, Min, Liu, Xiuheng, Chen, Zhiyuan, Chen, Hui, Tan, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798386/
https://www.ncbi.nlm.nih.gov/pubmed/35117220
http://dx.doi.org/10.21037/tcr-20-1186