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Cinnamophilin enhances temozolomide-induced cytotoxicity against malignant glioma: the roles of ROS and cell cycle arrest

BACKGROUND: Temozolomide (TMZ) has been widely used to treat glioblastoma multiforme (GBM). However, many mechanisms are known to quickly adapt GBM cells to chemotherapy with TMZ, leading to drug resistance and expansion of tumor cell populations. METHODS: We subjected human glioblastoma cell lines...

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Detalles Bibliográficos
Autores principales: Tai, Shih-Hang, Lin, Yu-Wen, Huang, Tung-Yi, Chang, Che-Chao, Chao, Liang-Chun, Wu, Tian-Shung, Lee, E-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798401/
https://www.ncbi.nlm.nih.gov/pubmed/35116690
http://dx.doi.org/10.21037/tcr-20-3426