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5-aza-2’-deoxycytidine (DAC) treatment induces the MAGE-A10 expression and improves the cytotoxicity of MAGE-A10-specific CTLs in lung cancer cells

BACKGROUND: MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. Epigenetic-modifying drugs can enhance the expression of tumo...

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Detalles Bibliográficos
Autores principales: Li, Zhenhua, Guo, Peng, Guo, Peiyuan, Dong, Keqin, Liu, Fei, Wu, Yunyan, Li, Juan, Shan, Baoen, Sang, Meixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798493/
https://www.ncbi.nlm.nih.gov/pubmed/35117468
http://dx.doi.org/10.21037/tcr.2020.01.10