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Denosumab inhibits MCF-7 cell line-induced spontaneous osteoclastogenesis via the RANKL/MALAT1/miR-124 axis

BACKGROUND: Denosumab is an inhibitor of receptor activator of NF-κB ligand (RANKL), which inhibits bone metastasis (BM) in breast cancer (BC), but does not completely control cancer cell BM in some BC patients. This study was designed to study whether denosumab inhibits human BC cells (MCF-7) cell...

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Detalles Bibliográficos
Autores principales: Feng, Qi, Wang, Donglai, Feng, Jiangang, Guo, Peng, Geng, Cuizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798509/
https://www.ncbi.nlm.nih.gov/pubmed/35117607
http://dx.doi.org/10.21037/tcr.2020.03.17