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CK1α-targeting inhibits primary and metastatic colorectal cancer in vitro, ex vivo, in cell-line-derived and patient-derived tumor xenograft mice models

BACKGROUND: Colorectal cancer (CRC) remains a leading cause of cancer-related deaths globally. Despite improved understanding of its initiation and progression, and advances in diagnostic or therapeutic strategies, the treatment of metastatic CRC remains a clinical challenge, necessitating identific...

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Detalles Bibliográficos
Autores principales: Ren, Fupeng, Zhu, Jingwen, Li, Kesang, Cheng, Yiquan, Zhu, Xiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798578/
https://www.ncbi.nlm.nih.gov/pubmed/35117537
http://dx.doi.org/10.21037/tcr.2020.02.13