Cargando…

CK1α-targeting inhibits primary and metastatic colorectal cancer in vitro, ex vivo, in cell-line-derived and patient-derived tumor xenograft mice models

BACKGROUND: Colorectal cancer (CRC) remains a leading cause of cancer-related deaths globally. Despite improved understanding of its initiation and progression, and advances in diagnostic or therapeutic strategies, the treatment of metastatic CRC remains a clinical challenge, necessitating identific...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Fupeng, Zhu, Jingwen, Li, Kesang, Cheng, Yiquan, Zhu, Xiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798578/ https://www.ncbi.nlm.nih.gov/pubmed/35117537 http://dx.doi.org/10.21037/tcr.2020.02.13

Ejemplares similares

Clinically relevant inflammatory breast cancer patient-derived xenograft–derived ex vivo model for evaluation of tumor-specific therapies
por: Eckhardt, Bedrich L., et al.
Publicado: (2018)

Cell Line Derived Xenograft Mouse Models Are a Suitable in vivo Model for Studying Tumor Budding in Colorectal Cancer
por: Georges, Laurent M. C., et al.
Publicado: (2019)

In Vivo Modeling of Human Breast Cancer Using Cell Line and Patient-Derived Xenografts
por: Souto, Eric P., et al.
Publicado: (2022)

Establishment of Novel Gastric Cancer Patient-Derived Xenografts and Cell Lines: Pathological Comparison between Primary Tumor, Patient-Derived, and Cell-Line Derived Xenografts
por: Kuwata, Takeshi, et al.
Publicado: (2019)

Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing
por: Brock, Rebecca M., et al.
Publicado: (2020)

Correction to: In Vivo Modeling of Human Breast Cancer Using Cell Line and Patient-Derived Xenografts
por: Souto, Eric P., et al.
Publicado: (2022)

A Biobank of Colorectal Cancer Patient-Derived Xenografts
por: Abdirahman, Suad M., et al.
Publicado: (2020)

Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts
por: Bhadury, Joydeep, et al.
Publicado: (2016)

Turmeric Is Therapeutic in Vivo on Patient-Derived Colorectal Cancer Xenografts: Inhibition of Growth, Metastasis, and Tumor Recurrence
por: Li, Mingyue, et al.
Publicado: (2021)

Overexpression of Nuclear Protein Kinase CK2 α Catalytic Subunit (CK2α) as a Poor Prognosticator in Human Colorectal Cancer
por: Lin, Kai-Yuan, et al.
Publicado: (2011)

CK1α overexpression correlates with poor survival in colorectal cancer
por: Richter, Julia, et al.
Publicado: (2018)

Murine Endogenous Retroviruses Are Detectable in Patient-Derived Xenografts but Not in Patient-Individual Cell Lines of Human Colorectal Cancer
por: Bock, Stephanie, et al.
Publicado: (2018)

An Immunohistochemical Expression of CK5/6, CK7, and CK20 on Cell Blocks in Metastatic Cervical Lymphadenopathy
por: Kaur, Amanpreet, et al.
Publicado: (2022)

A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases
por: Jian, Mi, et al.
Publicado: (2020)

Patient‐derived xenograft model in colorectal cancer basic and translational research
por: Liu, Xiaofeng, et al.
Publicado: (2022)

Preparation and application of patient-derived xenograft mice model of colorectal cancer
por: Zhang, Yutao, et al.
Publicado: (2023)

Human Metastatic Cholangiocarcinoma Patient-Derived Xenografts and Tumoroids for Preclinical Drug Evaluation
por: Serra-Camprubí, Queralt, et al.
Publicado: (2023)

Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts
por: Koessinger, Anna L., et al.
Publicado: (2020)

Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer
por: Dufait, Inès, et al.
Publicado: (2015)

Combined 5-FU and ChoKα Inhibitors as a New Alternative Therapy of Colorectal Cancer: Evidence in Human Tumor-Derived Cell Lines and Mouse Xenografts
por: de la Cueva, Ana, et al.
Publicado: (2013)

Development of the CK‐MB‐1 trastuzumab‐resistant HER2‐positive breast cancer cell line and xenograft animal models
por: Chung, Wei‐Pang, et al.
Publicado: (2021)

The Application of Patient-Derived Xenograft Models in Gynecologic Cancers
por: Jiang, Wenxiao, et al.
Publicado: (2020)

Tumour-Derived Cell Lines and Their Potential for Therapy Prediction in Patients with Metastatic Colorectal Cancer
por: Wagner, Sandra, et al.
Publicado: (2021)

Establishment and Characterization of 7 Novel Hepatocellular Carcinoma Cell Lines from Patient-Derived Tumor Xenografts
por: Xin, Hong, et al.
Publicado: (2014)

Patient-derived cell line, xenograft and organoid models in lung cancer therapy
por: Huo, Ku-Geng, et al.
Publicado: (2020)

Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models
por: Gock, Michael, et al.
Publicado: (2016)

Protocol for ex vivo culture of patient-derived tumor fragments
por: Roelofsen, Lisanne M., et al.
Publicado: (2023)

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts
por: Lieu, Christopher H., et al.
Publicado: (2015)

The burden of cervical cancer in China
por: Shen, Xiu, et al.
Publicado: (2022)

Comprehensive comparison of patient-derived xenograft models in Hepatocellular Carcinoma and metastatic Liver Cancer
por: Xu, Wei, et al.
Publicado: (2020)

Integrated Analysis of Transcriptome in Cancer Patient-Derived Xenografts
por: Li, Hong, et al.
Publicado: (2015)

Intraductal patient‐derived xenografts of estrogen receptor α‐positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions
por: Fiche, Maryse, et al.
Publicado: (2018)

Targeting Protein Kinases in Blood Cancer: Focusing on CK1α and CK2
por: Spinello, Zaira, et al.
Publicado: (2021)

Comprehensive characterization of the patient-derived xenograft and the paralleled primary hepatocellular carcinoma cell line
por: Cheung, Phyllis F. Y., et al.
Publicado: (2016)

Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract
por: Damhofer, Helene, et al.
Publicado: (2015)

Generation of novel patient-derived CIC-DUX4 sarcoma xenografts and cell lines
por: Oyama, Rieko, et al.
Publicado: (2017)

New generation breast cancer cell lines developed from patient-derived xenografts
por: Finlay-Schultz, Jessica, et al.
Publicado: (2020)

Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients
por: Morrison, Gladys, et al.
Publicado: (2016)

Capturing colorectal cancer inter‐tumor heterogeneity in patient‐derived xenograft (PDX) models
por: Prasetyanti, Pramudita R., et al.
Publicado: (2018)

Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research
por: Inoue, Akira, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1402dnv0746eo0fvng9f9na28q