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Sorafenib sensitizes melanoma cells to vemurafenib through ferroptosis
BACKGROUND: BRAF gene mutation causes melanoma patients to develop drug resistance after 8–9 months BRAF inhibitors treatment. Therefore, overcoming BRAF inhibitor resistance has important implications for improving patient survival. Sorafenib directly inhibits tumor cell proliferation by blocking t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798636/ https://www.ncbi.nlm.nih.gov/pubmed/35117506 http://dx.doi.org/10.21037/tcr.2020.01.62 |