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MicroRNA-153-3p sensitizes melanoma cells to dacarbazine by suppressing ATG5-mediated autophagy and apoptosis

BACKGROUND: Dacarbazine is one of the most commonly used chemotherapeutic agents for the treatment of melanoma; however, only 5–10% of patients benefit from this treatment. MicroRNA-153-3p (miR-153-3p) has a tumor-suppressive effect in melanoma. In the present study, we found that miR-153-3p was dow...

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Detalles Bibliográficos
Autores principales: Hou, Shaowei, Guo, Minfang, Xi, Haiying, Zhang, Lianqing, Zhao, Ailing, Hou, Heng, Fang, Wuning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798736/
https://www.ncbi.nlm.nih.gov/pubmed/35117926
http://dx.doi.org/10.21037/tcr-20-2660