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Phase 1 dose-escalation study of apatinib and irinotecan in esophageal squamous cell carcinoma patients
BACKGROUND: Apatinib, an inhibitor of vascular endothelial growth factor receptor (VEGFR), has been used to treat esophagogastric adenocarcinoma. However, the dosage of apatinib varies greatly in clinical practice, and its safety in esophageal squamous cell carcinoma (ESCC) patients is unclear. Ther...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798775/ https://www.ncbi.nlm.nih.gov/pubmed/35116396 http://dx.doi.org/10.21037/tcr-20-2492 |