Oridonin enhances the anti-tumor activity of gemcitabine towards pancreatic cancer by stimulating Bax- and Smac-dependent apoptosis

BACKGROUND: Oridonin has been shown to exhibit potent anti-tumor activity, but the exact mechanisms underlying this activity remains unclear. Here, we investigated whether oridonin could synergistically enhance the activity of gemcitabine against BxPC-3 pancreatic cancer cells. METHODS: CCK-8 assays...

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Detalles Bibliográficos
Autores principales: Liu, Dian-Lei, Bu, He-Qi, Wang, Wen-Long, Luo, Hua, Cheng, Bo-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798810/
https://www.ncbi.nlm.nih.gov/pubmed/35117784
http://dx.doi.org/10.21037/tcr-19-3000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798810/
https://www.ncbi.nlm.nih.gov/pubmed/35117784
http://dx.doi.org/10.21037/tcr-19-3000

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