Cargando…

Protein tyrosine phosphatase receptor type delta (PTPRD) suppresses the expression of PD-L1 in human hepatocellular carcinoma by down-regulating STAT3

BACKGROUND: Protein tyrosine phosphatase receptor type delta (PTPRD) is a tumor suppressor that is often inactivated in hepatocellular carcinoma (HCC). However, the mechanisms of how PTPRD inhibits HCC are not well understood. Programmed cell death ligand 1 (PD-L1), an immune checkpoint, plays a sem...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Qiuhua, Tian, Jing, Qin, Feizhang, Huang, Xuejing, Zhu, Dan, Xiang, Bangde, Dong, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798851/
https://www.ncbi.nlm.nih.gov/pubmed/35117921
http://dx.doi.org/10.21037/tcr-20-2425