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Protein tyrosine phosphatase receptor type delta (PTPRD) suppresses the expression of PD-L1 in human hepatocellular carcinoma by down-regulating STAT3

BACKGROUND: Protein tyrosine phosphatase receptor type delta (PTPRD) is a tumor suppressor that is often inactivated in hepatocellular carcinoma (HCC). However, the mechanisms of how PTPRD inhibits HCC are not well understood. Programmed cell death ligand 1 (PD-L1), an immune checkpoint, plays a sem...

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Detalles Bibliográficos
Autores principales:	Meng, Qiuhua, Tian, Jing, Qin, Feizhang, Huang, Xuejing, Zhu, Dan, Xiang, Bangde, Dong, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798851/ https://www.ncbi.nlm.nih.gov/pubmed/35117921 http://dx.doi.org/10.21037/tcr-20-2425

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