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Cinobufagin inhibits tumor growth by inducing apoptosis through Notch signaling pathways in human cholangiocarcinoma

BACKGROUND: Many studies have shown that cinobufagin has antitumor effects against many cancers. The aim of this study was to assess the effects of cinobufagin on cholangiocarcinoma (CCA) cells. METHODS: Colony formation assay, cell-counting kit-8 (CCK-8) assay, and tumor xenograft experiments were...

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Detalles Bibliográficos
Autores principales: Ren, Jiajun, Wang, Shouhua, Jin, Longyang, Ma, Fei, Zhou, Di, Cai, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798894/
https://www.ncbi.nlm.nih.gov/pubmed/35116998
http://dx.doi.org/10.21037/tcr.2019.10.06