NUMB knockdown enhanced the anti-tumor role of cisplatin on ovarian cancer cells by inhibiting cell proliferation and epithelial-mesenchymal transition

BACKGROUND: NUMB is an inhibitory regulator of NOTCH signaling, which is critical for the induction of epithelial-mesenchymal transition (EMT). Loss of NUMB expression is correlated with the genesis and development of multiple tumors. Recent studies reported that NUMB expression was upregulated in h...

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Detalles Bibliográficos
Autores principales: Liu, Zhao, Qi, Shasha, Fu, Yibing, Shen, Liang, Li, Mingjiang, Lu, Jiaju, Zhao, Xingbo, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798962/
https://www.ncbi.nlm.nih.gov/pubmed/35116770
http://dx.doi.org/10.21037/tcr.2019.01.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798962/
https://www.ncbi.nlm.nih.gov/pubmed/35116770
http://dx.doi.org/10.21037/tcr.2019.01.35

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