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Efficacy of newly discovered DNA aptamers targeting AXL in a lung cancer cell with acquired resistance to Erlotinib

BACKGROUND: Accumulating evidences indicate that AXL overexpression or activation is associated with cancer progression and acquired resistance to targeted anti-cancer drugs such as epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Despite recent development of several drugs t...

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Detalles Bibliográficos
Autores principales: Hwang, Ji An, Hur, Jae Young, Kim, Youndong, Im, Jong Hun, Jin, Seong Hui, Ryu, Sung Ho, Choi, Chang-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798984/
https://www.ncbi.nlm.nih.gov/pubmed/35116429
http://dx.doi.org/10.21037/tcr-20-2447