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Hypoxia induces tumor cell growth and angiogenesis in non-small cell lung carcinoma via the Akt-PDK1-HIF1α-YKL-40 pathway

BACKGROUND: As one of the most common forms of cancer, non-small cell lung carcinoma (NSCLC), is characterized by oxygen deprivation (hypoxia). The transcription factor hypoxia-inducible factor (HIF)-1α is a major mediator which responds hypoxia and regulates many contributing factors. The various m...

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Detalles Bibliográficos
Autores principales: Miao, Yushan, Wang, Wei, Dong, Yaping, Hu, Jiaxun, Wei, Kunchen, Yang, Shuo, Lai, Xueli, Tang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799056/
https://www.ncbi.nlm.nih.gov/pubmed/35117647
http://dx.doi.org/10.21037/tcr.2020.03.80