Limonin inhibits angiogenesis and metastasis of human breast cancer cells by suppressing the VEGFR2/IGFR1-mediated STAT3 signaling pathway

BACKGROUND: Limonin is one of the major active ingredients of citrus. In the present study, the anti-angiogenic and anti-metastatic effects of limonin were investigated. METHODS: The Molecular docking assay was carried out to assess the binding ability of limonin with VEGFR2 receptor. MTS assay was...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Liu, Bo-Xia, Shen, Qin, Li, Na, Ling, Jun, Xiao, Min, Jiao, Hai-Yan, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799072/
https://www.ncbi.nlm.nih.gov/pubmed/35117291
http://dx.doi.org/10.21037/tcr-20-1992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799072/
https://www.ncbi.nlm.nih.gov/pubmed/35117291
http://dx.doi.org/10.21037/tcr-20-1992

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