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PRC1 promotes cell proliferation and cell cycle progression by regulating p21/p27-pRB family molecules and FAK-paxillin pathway in non-small cell lung cancer

BACKGROUND: This study aimed to demonstrate the function and molecular mechanism of protein regulator of cytokinesis 1 (PRC1) in the carcinogenesis of non-small cell lung cancer (NSCLC). METHODS: Bioinformatics analysis was performed. Cell culture and plasmid construction were conducted for cell tra...

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Detalles Bibliográficos
Autores principales: Liang, Zhigang, Li, Xinjian, Chen, Jian, Cai, Haina, Zhang, Liqun, Li, Chenwei, Tong, Jingjie, Hu, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799135/
https://www.ncbi.nlm.nih.gov/pubmed/35116955
http://dx.doi.org/10.21037/tcr.2019.09.19