Cargando…

PRC1 promotes cell proliferation and cell cycle progression by regulating p21/p27-pRB family molecules and FAK-paxillin pathway in non-small cell lung cancer

BACKGROUND: This study aimed to demonstrate the function and molecular mechanism of protein regulator of cytokinesis 1 (PRC1) in the carcinogenesis of non-small cell lung cancer (NSCLC). METHODS: Bioinformatics analysis was performed. Cell culture and plasmid construction were conducted for cell tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Zhigang, Li, Xinjian, Chen, Jian, Cai, Haina, Zhang, Liqun, Li, Chenwei, Tong, Jingjie, Hu, Wentao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799135/ https://www.ncbi.nlm.nih.gov/pubmed/35116955 http://dx.doi.org/10.21037/tcr.2019.09.19

Ejemplares similares

Cell cycle regulators p27 and pRb in lymphomas – correlation with histology and proliferative activity
por: Kiviniemi, M, et al.
Publicado: (2000)

p16, pRb, and p53 in Feline Oral Squamous Cell Carcinoma
por: Supsavhad, Wachiraphan, et al.
Publicado: (2016)

p130 And pRb in the Maintenance of Transient Quiescence of Mesenchymal Stem Cells
por: Popov, Boris, et al.
Publicado: (2020)

Relevance of pRB Loss in Human Malignancies
por: Mandigo, Amy C., et al.
Publicado: (2022)

pRB-Depleted Pluripotent Stem Cell Retinal Organoids Recapitulate Cell State Transitions of Retinoblastoma Development and Suggest an Important Role for pRB in Retinal Cell Differentiation
por: Rozanska, Agata, et al.
Publicado: (2022)

Aberrant Expression of pRb, p16, p14ARF, MDM2, p21 and p53 in Squamous Cell Carcinomas of Lung
por: Xue, Qi, et al.
Publicado: (2001)

Polyomavirus-Associated Trichodysplasia Spinulosa Involves Hyperproliferation, pRB Phosphorylation and Upregulation of p16 and p21
por: Kazem, Siamaque, et al.
Publicado: (2014)

Roles of pRB in the Regulation of Nucleosome and Chromatin Structures
por: Uchida, Chiharu
Publicado: (2016)

Antitumor mechanisms when pRb and p53 are genetically inactivated
por: Zhu, Liang, et al.
Publicado: (2014)

Treating cancer when pRb and p53 cannot be reactivated
por: Zhu, Liang
Publicado: (2015)

Loss of functional pRB is not a ubiquitous feature of B-cell malignancies
por: Sinclair, A J, et al.
Publicado: (1999)

Involvement of pRB family in TGF beta-dependent epithelial cell hypertrophy
Publicado: (1995)

CENPA overexpression promotes genome instability in pRb-depleted human cells
por: Amato, Angela, et al.
Publicado: (2009)

Inhibition of pRB Pathway Differentially Modulates Apoptosis in Esophageal Cancer Cells
por: Soletti, Rossana C., et al.
Publicado: (2017)

Phosphorylation of pRb: mechanism for RB pathway inactivation in MYCN‐amplified retinoblastoma
por: Ewens, Kathryn G., et al.
Publicado: (2017)

Simultaneous Analysis of the p16 Gene and Protein in Canine Lymphoma Cells and Their Correlation with pRb Phosphorylation
por: Maylina, Leni, et al.
Publicado: (2022)

pRb or its cousins: Who controls the family business?
por: Itahana, Koji, et al.
Publicado: (2012)

pRB immunostaining in the differential diagnosis between pleomorphic xanthoastrocytoma and glioblastoma with giant cells
por: Barresi, Valeria, et al.
Publicado: (2022)

Deficiency of G1 regulators P53, P21(Cip1 )and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest
por: Sheahan, Sharon, et al.
Publicado: (2007)

Prediction of progression in pTa and pT1 bladder carcinomas with p53, p16 and pRb
por: Hitchings, A W, et al.
Publicado: (2004)

Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines
por: Huun, Johanna, et al.
Publicado: (2017)

The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence
por: Haferkamp, Sebastian, et al.
Publicado: (2009)

pRb controls Estrogen Receptor alpha protein stability and activity
por: Caligiuri, Isabella, et al.
Publicado: (2013)

Cell cycle-dependent phosphorylation of pRb-like protein in root meristem cells of Vicia faba
por: Polit, Justyna Teresa, et al.
Publicado: (2011)

Molecular Signature of HPV-Induced Carcinogenesis: pRb, p53 and Gene Expression Profiling
por: Buitrago-Pérez, Águeda, et al.
Publicado: (2009)

Expression of pRb, p53, p16 and Cyclin D1 and Their Clinical Implications in Urothelial Carcinoma
por: Lee, Kyungji, et al.
Publicado: (2010)

Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb
por: Vietri, Michele, et al.
Publicado: (2006)

Combined Inactivation of pRB and Hippo Pathways Induces Dedifferentiation in the Drosophila Retina
por: Nicolay, Brandon N., et al.
Publicado: (2010)

CDK4, pRB and E2F1: connected to insulin
por: Fajas, Lluis, et al.
Publicado: (2010)

pRb-mediated control of epithelial cell proliferation and Indian Hedgehog expression in mouse intestinal development
por: Yang, Hai-Su, et al.
Publicado: (2007)

pRb Inactivation in Mammary Cells Reveals Common Mechanisms for Tumor Initiation and Progression in Divergent Epithelia
por: Simin, Karl, et al.
Publicado: (2004)

A pRb-independent mechanism preserves the postmitotic state in terminally differentiated skeletal muscle cells
por: Camarda, Grazia, et al.
Publicado: (2004)

Merkel cell polyomavirus large T antigen binding to pRb promotes skin hyperplasia and tumor development
por: Spurgeon, Megan E., et al.
Publicado: (2022)

Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma
por: Plath, Michaela, et al.
Publicado: (2018)

pRb-E2F signaling in life of mesenchymal stem cells: Cell cycle, cell fate, and cell differentiation
por: Popov, Boris, et al.
Publicado: (2014)

FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest
por: Laplantine, Emmanuel, et al.
Publicado: (2002)

Human papillomavirus infection and immunohistochemical expression of cell cycle proteins pRb, p53, and p16(INK4a) in sinonasal diseases
por: Yamashita, Yukashi, et al.
Publicado: (2015)

Cyclin D1 expression in transitional cell carcinoma of the bladder: correlation with p53, waf1, pRb and Ki67
por: Tut, V M, et al.
Publicado: (2001)

RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells
por: Carper, Miranda B., et al.
Publicado: (2014)

Expression of Cell-Cycle Regulatory Proteins pRb, Cyclin D1, and p53 Is Not Associated with Recurrence Rates of Equine Sarcoids
por: Tura, Giorgia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kucuvicvts4e67jst8lulp5koc