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The Notch1 gene may control cell chemoresistance in esophageal squamous cell cancer

BACKGROUND: In our previous study, missense mutations in the Notch1 gene were found in chemotherapy-resistant esophageal squamous cell cancer (ESCC) patients. In this study, we explored changes in the interaction between Notch1 and DLL4 resulting from missense mutations. METHODS: Bioinformatics anal...

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Detalles Bibliográficos
Autores principales: Gao, Kun, Xing, Wenqun, Liu, Xianben, Liu, Jizhao, Sun, Haibo, Hao, Wentao, Zheng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799163/
https://www.ncbi.nlm.nih.gov/pubmed/35116634
http://dx.doi.org/10.21037/tcr-21-447