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KDELR2 knockdown synergizes with temozolomide to induce glioma cell apoptosis through the CHOP and JNK/p38 pathways

BACKGROUND: The C-terminal tetrapeptide Lys-Asp-Glu-Leu receptors (KDELRs) are transmembrane proteins that regulate ER stress (ERS) response, growth, differentiation, and immune responses. There is an association between KDELR2and promotion of glioblastoma tumorigenesis. The aim of the present study...

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Detalles Bibliográficos
Autores principales: Zhang, Guofeng, Wang, Bin, Cheng, Shiqi, Fan, Hengyi, Liu, Shaowen, Zhou, Bin, Liu, Weibin, Liang, Rui, Tang, Youjia, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799170/
https://www.ncbi.nlm.nih.gov/pubmed/35116653
http://dx.doi.org/10.21037/tcr-21-869