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Is there an efficacy-effectiveness gap between randomized controlled trials and real-world studies in colorectal cancer: a systematic review and meta-analysis

BACKGROUND: To investigate whether patients with colorectal cancer (CRC) enrolled in randomized controlled trials (RCTs) and real-world studies (RWS) differ in terms of baseline characteristics, leading to an efficacy-effectiveness gap. METHODS: A systematic literature reviews was conducted to ident...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Fu, Shihui, Meng, Rui, Ren, Yu, Shang, Ye, Tian, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799209/
https://www.ncbi.nlm.nih.gov/pubmed/35117304
http://dx.doi.org/10.21037/tcr-20-2303