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ET-1 promotes the growth and metastasis of esophageal squamous cell carcinoma via activating PI3K/Akt pathway

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the prevalent and deadly cancers worldwide. Previous studies confirmed that endothelin-1 (ET-1) serves as an oncogene and therapeutic target in various tumors. However, the role and mechanism of ET-1 in the progression of ESCC remains l...

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Detalles Bibliográficos
Autores principales: Yin, Hui, Wang, Lunqing, Li, Fei, Wang, Dongfei, Zhang, Zhe, Yu, Bentong, Liu, Yange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799244/
https://www.ncbi.nlm.nih.gov/pubmed/35117695
http://dx.doi.org/10.21037/tcr.2020.04.26