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Wild-type isocitrate dehydrogenase under the spotlight in glioblastoma

Brain tumors actively reprogram their cellular metabolism to survive and proliferate, thus offering potential therapeutic opportunities. Over the past decade, extensive research has been done on mutant IDH enzymes as markers of good prognosis in glioblastoma, a highly aggressive brain tumor in adult...

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Detalles Bibliográficos
Autores principales: Alzial, Gabriel, Renoult, Ophelie, Paris, François, Gratas, Catherine, Clavreul, Anne, Pecqueur, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799461/
https://www.ncbi.nlm.nih.gov/pubmed/34764443
http://dx.doi.org/10.1038/s41388-021-02056-1