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Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis

Autophagy is an essential catabolic process that orchestrates cellular homeostasis and plays dual roles in tumor promotion and suppression. However, the mechanism by which autophagy affects the self-renewal of cancer stem cells (CSCs) remains unclear. In this study, we investigated whether autophagy...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Zhao, Hui, Liang, Weilian, Jiang, Erhui, Zhou, Xiaocheng, Shao, Zhe, Liu, Ke, Shang, Zhengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799462/
https://www.ncbi.nlm.nih.gov/pubmed/34795388
http://dx.doi.org/10.1038/s41388-021-02115-7