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Epigenetic moderators of naltrexone efficacy in reducing heavy drinking in Alcohol Use Disorder: A randomized trial

Polymorphisms in genes associated with opioid signaling and dopamine reuptake and inactivation may moderate naltrexone efficacy in Alcohol Use Disorder (AUD), but the effects of epigenetic modification of these genes on naltrexone response are largely unexplored. This study tested interactions betwe...

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Detalles Bibliográficos
Autores principales: Schacht, Joseph P., Hoffman, Michaela, Chen, Brian H., Anton, Raymond F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799481/
https://www.ncbi.nlm.nih.gov/pubmed/34381173
http://dx.doi.org/10.1038/s41397-021-00250-8