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Quinone binding in respiratory complex I: Going through the eye of a needle. The squeeze-in mechanism of passing the narrow entrance of the quinone site

At the joint between the membrane and hydrophilic arms of the enzyme, the structure of the respiratory complex I reveals a tunnel-like Q-chamber for ubiquinone binding and reduction. The narrow entrance of the quinone chamber located in ND1 subunit forms a bottleneck (eye of a needle) which in all r...

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Detalles Bibliográficos
Autores principales: Dhananjayan, Nithin, Wang, Panyue, Leontyev, Igor, Stuchebrukhov, Alexei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799541/
https://www.ncbi.nlm.nih.gov/pubmed/34813075
http://dx.doi.org/10.1007/s43630-021-00113-y