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Quinone binding in respiratory complex I: Going through the eye of a needle. The squeeze-in mechanism of passing the narrow entrance of the quinone site
At the joint between the membrane and hydrophilic arms of the enzyme, the structure of the respiratory complex I reveals a tunnel-like Q-chamber for ubiquinone binding and reduction. The narrow entrance of the quinone chamber located in ND1 subunit forms a bottleneck (eye of a needle) which in all r...
Autores principales: | Dhananjayan, Nithin, Wang, Panyue, Leontyev, Igor, Stuchebrukhov, Alexei A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799541/ https://www.ncbi.nlm.nih.gov/pubmed/34813075 http://dx.doi.org/10.1007/s43630-021-00113-y |
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