A general synthesis of azetidines by copper-catalysed photoinduced anti-Baldwin radical cyclization of ynamides

A general anti-Baldwin radical 4-exo-dig cyclization from nitrogen-substituted alkynes is reported. Upon reaction with a heteroleptic copper complex in the presence of an amine and under visible light irradiation, a range of ynamides were shown to smoothly cyclize to the corresponding azetidines, us...

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Detalles Bibliográficos
Autores principales: Jacob, Clément, Baguia, Hajar, Dubart, Amaury, Oger, Samuel, Thilmany, Pierre, Beaudelot, Jérôme, Deldaele, Christopher, Peruško, Stefano, Landrain, Yohann, Michelet, Bastien, Neale, Samuel, Romero, Eugénie, Moucheron, Cécile, Van Speybroeck, Veronique, Theunissen, Cédric, Evano, Gwilherm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799647/
https://www.ncbi.nlm.nih.gov/pubmed/35091551
http://dx.doi.org/10.1038/s41467-022-28098-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799647/
https://www.ncbi.nlm.nih.gov/pubmed/35091551
http://dx.doi.org/10.1038/s41467-022-28098-x

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