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Accumulation of microbial DNAs promotes to islet inflammation and β cell abnormalities in obesity in mice
Various microbial products leaked from gut lumen exacerbate tissue inflammation and metabolic disorders in obesity. Vsig4+ macrophages are key players preventing infiltration of bacteria and their products into host tissues. However, roles of islet Vsig4+ macrophages in the communication between mic...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799656/ https://www.ncbi.nlm.nih.gov/pubmed/35091566 http://dx.doi.org/10.1038/s41467-022-28239-2 |