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Accumulation of microbial DNAs promotes to islet inflammation and β cell abnormalities in obesity in mice

Various microbial products leaked from gut lumen exacerbate tissue inflammation and metabolic disorders in obesity. Vsig4+ macrophages are key players preventing infiltration of bacteria and their products into host tissues. However, roles of islet Vsig4+ macrophages in the communication between mic...

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Detalles Bibliográficos
Autores principales: Gao, Hong, Luo, Zhenlong, Ji, Yudong, Tang, Kechun, Jin, Zhongmou, Ly, Crystal, Sears, Dorothy D., Mahata, Sushil, Ying, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799656/
https://www.ncbi.nlm.nih.gov/pubmed/35091566
http://dx.doi.org/10.1038/s41467-022-28239-2