MITF activity is regulated by a direct interaction with RAF proteins in melanoma cells

The MITF transcription factor and the RAS/RAF/MEK/ERK pathway are two interconnected main players in melanoma. Understanding how MITF activity is regulated represents a key question since its dynamic modulation is involved in the phenotypic plasticity of melanoma cells and their resistance to therap...

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Detalles Bibliográficos
Autores principales: Estrada, Charlène, Mirabal-Ortega, Liliana, Méry, Laurence, Dingli, Florent, Besse, Laetitia, Messaoudi, Cedric, Loew, Damarys, Pouponnot, Celio, Bertolotto, Corine, Eychène, Alain, Druillennec, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799692/
https://www.ncbi.nlm.nih.gov/pubmed/35091687
http://dx.doi.org/10.1038/s42003-022-03049-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799692/
https://www.ncbi.nlm.nih.gov/pubmed/35091687
http://dx.doi.org/10.1038/s42003-022-03049-w

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