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Pharmacological targeting PIKfyve and tubulin as an effective treatment strategy for double-hit lymphoma

Double-hit lymphoma is one of the most aggressive and refractory lymphoma subtypes with recurrent genetic abnormalities of MYC and BCL-2 or BCL6 rearrangement, leading to a poor prognosis in the present clinical practice. Therefore, new therapeutic strategies for eliminating double-hit lymphomas are...

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Detalles Bibliográficos
Autores principales: Feng, Liying, Chen, Kai, Huang, Wei, Jiang, Yuelong, Sun, Xihuan, Zhou, Yong, Li, Li, Li, Yin, Deng, Xianming, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799717/
https://www.ncbi.nlm.nih.gov/pubmed/35091546
http://dx.doi.org/10.1038/s41420-022-00833-9