Epigenomic and transcriptomic analyses reveal differences between low-grade inflammation and severe exhaustion in LPS-challenged murine monocytes

Emerging studies suggest that monocytes can be trained by bacterial endotoxin to adopt distinct memory states ranging from low-grade inflammation to immune exhaustion. While low-grade inflammation may contribute to the pathogenesis of chronic diseases, exhausted monocytes with pathogenic and immune-...

Descripción completa

Detalles Bibliográficos
Autores principales: Naler, Lynette B., Hsieh, Yuan-Pang, Geng, Shuo, Zhou, Zirui, Li, Liwu, Lu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799722/
https://www.ncbi.nlm.nih.gov/pubmed/35091696
http://dx.doi.org/10.1038/s42003-022-03035-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799722/
https://www.ncbi.nlm.nih.gov/pubmed/35091696
http://dx.doi.org/10.1038/s42003-022-03035-2

Ejemplares similares