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The cGAS–STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and deranged signaling of the cGAS–STING axis is closely i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799861/ https://www.ncbi.nlm.nih.gov/pubmed/35127372 http://dx.doi.org/10.1016/j.apsb.2021.05.011 |