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The cGAS–STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy

The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and deranged signaling of the cGAS–STING axis is closely i...

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Detalles Bibliográficos
Autores principales: Oduro, Patrick Kwabena, Zheng, Xianxian, Wei, Jinna, Yang, Yanze, Wang, Yuefei, Zhang, Han, Liu, Erwei, Gao, Xiumei, Du, Mei, Wang, Qilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799861/
https://www.ncbi.nlm.nih.gov/pubmed/35127372
http://dx.doi.org/10.1016/j.apsb.2021.05.011