Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis

Phosphodiesterase-4 (PDE4) functions as a catalyzing enzyme targeting hydrolyzation of intracellular cyclic adenosine monophosphate (cAMP) and inhibition of PDE4 has been proven to be a competitive strategy for dermatological and pulmonary inflammation. However, the pathological role of PDE4 and the...

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Detalles Bibliográficos
Autores principales: Li, Heng, Zhang, Yao, Liu, Moting, Fan, Chen, Feng, Chunlan, Lu, Qiukai, Xiang, Caigui, Lu, Huimin, Yang, Xiaoqian, Wu, Bing, Zou, Duowu, Tang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799862/
https://www.ncbi.nlm.nih.gov/pubmed/35127382
http://dx.doi.org/10.1016/j.apsb.2021.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799862/
https://www.ncbi.nlm.nih.gov/pubmed/35127382
http://dx.doi.org/10.1016/j.apsb.2021.04.007

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