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[(18)F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models

Monoacylglycerol lipase (MAGL) is a pivotal enzyme in the endocannabinoid system, which metabolizes 2-arachidonoylglycerol (2-AG) into the proinflammatory eicosanoid precursor arachidonic acid (AA). MAGL and other endogenous cannabinoid (EC) degrading enzymes are involved in the fibrogenic signaling...

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Detalles Bibliográficos
Autores principales: Shao, Tuo, Chen, Zhen, Rong, Jian, Belov, Vasily, Chen, Jiahui, Jeyarajan, Andre, Deng, Xiaoyun, Fu, Hualong, Yu, Qingzhen, Rwema, Steve H., Lin, Wenyu, Papisov, Mikhail, Josephson, Lee, Chung, Raymond T., Liang, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799882/
https://www.ncbi.nlm.nih.gov/pubmed/35127387
http://dx.doi.org/10.1016/j.apsb.2021.07.007