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[(18)F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models
Monoacylglycerol lipase (MAGL) is a pivotal enzyme in the endocannabinoid system, which metabolizes 2-arachidonoylglycerol (2-AG) into the proinflammatory eicosanoid precursor arachidonic acid (AA). MAGL and other endogenous cannabinoid (EC) degrading enzymes are involved in the fibrogenic signaling...
Autores principales: | Shao, Tuo, Chen, Zhen, Rong, Jian, Belov, Vasily, Chen, Jiahui, Jeyarajan, Andre, Deng, Xiaoyun, Fu, Hualong, Yu, Qingzhen, Rwema, Steve H., Lin, Wenyu, Papisov, Mikhail, Josephson, Lee, Chung, Raymond T., Liang, Steven H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799882/ https://www.ncbi.nlm.nih.gov/pubmed/35127387 http://dx.doi.org/10.1016/j.apsb.2021.07.007 |
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