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Bridging the structure gap between pellets in artificial dissolution media and in gastro-intestinal tract in rats

Changes in structure of oral solid dosage forms (OSDF) elementally determine the drug release and its therapeutic effects. In this research, synchrotron radiation X-ray micro-computed tomography was utilized to visualize the 3D structure of enteric coated pellets recovered from the gastrointestinal...

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Detalles Bibliográficos
Autores principales: Sun, Hongyu, He, Siyu, Wu, Li, Cao, Zeying, Sun, Xian, Xu, Mingwei, Lu, Shan, Xu, Mingdi, Ning, Baoming, Sun, Huimin, Xiao, Tiqiao, York, Peter, Xu, Xu, Yin, Xianzhen, Zhang, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799995/
https://www.ncbi.nlm.nih.gov/pubmed/35127389
http://dx.doi.org/10.1016/j.apsb.2021.05.010